Weight gain and integrase inhibitors

Patterns of Maternal Weight Gain During Pregnancy and Birth Weight

Anthropometric parameters are an important indicator of health and nutritional status comprising the whole span of mans life. However, they are not of the same degree of simplicity and sensitivity in assessing the public health status. During recent decades many studies have attempted to examine the relationships of these measurements in order to present simple alternatives for similar purposes...

Patterns of Weight Gain and Birth Weight Amongst Indian Women

Background: The timing of maternal weight change in pregnancy may be an important determinant of birth weight. The objective of this study was to measure weight gain patterns from early pregnancy until delivery, and to examine the relationship between prenatal weight gain and low birth weight. Methods: A total of 500 pregnant women within 15-20 days of conception, with confirmed pregnancies and...

Resistance to Integrase Inhibitors

Integrase (IN) is a clinically validated target for the treatment of human immunodeficiency virus infections and raltegravir exhibits remarkable clinical activity. The next most advanced IN inhibitor is elvitegravir. However, mutant viruses lead to treatment failure and mutations within the IN coding sequence appear to confer cross-resistance. The characterization of those mutations is critical...

Weight Gain After Switch from Efavirenz-Based to Integrase Inhibitor-Based Regimens

Hysterectomy and weight gain.

OBJECTIVE To investigate whether overweight women are more likely to have a hysterectomy and whether hysterectomy leads to increased weight gain. METHODS Survey data of middle-aged women participating in the Australian Longitudinal Study on Women's health in 1996 (ages 45-50 y; n = 13,125), 1998 (n = 10,612), 2001 (n = 10,293), and 2004 (n = 9309) included self-reported height, weight, and hy...